Split-plot Central Composite Experimental Design Method for Optimization of Cake Height to Achieve desired Texture

Central composite experimental design applied to fabrication of LLDPE microporous membrane via thermally induced phase separation (TIPS) method

Application of Central Composite Design for Optimization of Coacervative Extraction of Cu(II) Using Anionic Surfactant

The aim of this work was to develop a new and simple coacervative extraction method for the preconcentration and spectrophotometric determination of Cu(II) in water samples. Dithizone was used as the chelating agent while an anionic surfactant, namely sodium dodecyl sulfate (SDS), was used as extracting agent at room temperature. Central composite design (CCD) based on response surface methodol...

Central Composite experimental design applied to removal of phenanthrene and acenaphthene from soil samples

Abstract In this work, removal of phenanthrene and acenaphthene, as a representative of polycyclic aromatic hydrocarbons, was investigated from soil samples by the soil washing remediation method combined with Central Composite Design. Response surface methodology was utilized to investigate the individual and interactive effects of three variables of removal process including surfactant solut...

Incorporating Cost and Optimizing Central Composite Designs for Split - Plot Response Surface Methodology Experiments

Complete randomization in many industrial and agricultural experiments is frequently impractical due to constraints in time, cost or existence of one or more hard-to-change factors. In these situations, restrictions on randomization lead to split-plot designs (SPD), allowing certain factor levels to be randomly applied to the whole plot units and remaining factor levels randomly to the subplot ...

Multi-response optimization of Artemia hatching process using split-split-plot design based response surface methodology

A novel method, BBD-SSPD is proposed by the combination of Box-Behnken Design (BBD) and Split-Split Plot Design (SSPD) which would ensure minimum number of experimental runs, leading to economical utilization in multi- factorial experiments. The brine shrimp Artemia was tested to study the combined effects of photoperiod, temperature and salinity, each with three levels, on the hatching percent...